:root {
            --primary-color: #2c7da0;
            --secondary-color: #a9d6e5;
            --accent-color: #01497c;
            --light-gray: #f8f9fa;
            --border-color: #eaeaea;
            --text-color: #333;
            --text-muted: #6c757d;
            --success-color: #28a745;
            --warning-color: #ffc107;
            --medical-red: #dc3545;
            --medical-green: #198754;
            --medical-yellow: #ffc107;
            --medical-orange: #fd7e14;
            --ecology-green: #198754;
            --ecology-blue: #0d6efd;
            --ecology-purple: #6f42c1;
        }
 
        .diversity-alert {
            background-color: rgba(25, 135, 84, 0.1);
            border-left: 4px solid var(--ecology-green);
            padding: 1rem;
            margin: 1rem 0;
            border-radius: 0 4px 4px 0;
        }
        
        .diversity-level {
            padding: 1rem;
            border-radius: 8px;
            margin: 1rem 0;
            border-left: 5px solid;
        }
        
        .diversity-low {
            background-color: rgba(220, 53, 69, 0.1);
            border-left-color: var(--medical-red);
        }
        
        .diversity-moderate {
            background-color: rgba(255, 193, 7, 0.1);
            border-left-color: var(--medical-yellow);
        }
        
        .diversity-high {
            background-color: rgba(25, 135, 84, 0.1);
            border-left-color: var(--ecology-green);
        }
        
        .diversity-very-high {
            background-color: rgba(13, 110, 253, 0.1);
            border-left-color: var(--ecology-blue);
        }
        
        .diversity-chart-container {
            position: relative;
            height: 300px;
            width: 100%;
            margin: 1.5rem 0;
        }
        
        .diversity-indicator {
            display: inline-block;
            width: 12px;
            height: 12px;
            border-radius: 50%;
            margin-right: 8px;
        }
        
        .indicator-low {
            background-color: var(--medical-red);
        }
        
        .indicator-moderate {
            background-color: var(--medical-yellow);
        }
        
        .indicator-high {
            background-color: var(--ecology-green);
        }
        
        .indicator-very-high {
            background-color: var(--ecology-blue);
        }
        
        .species-row {
            display: flex;
            align-items: center;
            margin-bottom: 0.75rem;
            padding: 0.5rem;
            border-radius: 4px;
            background-color: rgba(44, 125, 160, 0.05);
        }
        
        .species-row:hover {
            background-color: rgba(44, 125, 160, 0.1);
        }
        
        .species-name {
            flex: 1;
            font-weight: 500;
        }
        
        .species-abundance {
            width: 100px;
            text-align: right;
        }
        
        .remove-species {
            margin-left: 1rem;
            color: var(--medical-red);
            cursor: pointer;
        }
        
        .generating-indicator {
            display: none;
            text-align: center;
            padding: 1rem;
            color: var(--text-muted);
        }
        
        .reference-table {
            width: 100%;
            border-collapse: collapse;
            margin: 1.5rem 0;
        }
        
        .reference-table th, .reference-table td {
            padding: 0.75rem;
            text-align: left;
            border: 1px solid var(--border-color);
        }
        
        .reference-table th {
            background-color: var(--light-gray);
            font-weight: 600;
        }
        
        .reference-table tr:nth-child(even) {
            background-color: rgba(44, 125, 160, 0.05);
        }
        
        .real-time-indicator {
            display: none;
            position: absolute;
            top: 10px;
            right: 10px;
            background-color: var(--primary-color);
            color: white;
            padding: 4px 8px;
            border-radius: 4px;
            font-size: 0.75rem;
            font-weight: 600;
        }
        
        .result-container.has-real-time .real-time-indicator {
            display: block;
        }
        
        .sample-comparison {
            display: grid;
            grid-template-columns: 1fr 1fr;
            gap: 1.5rem;
            margin: 1.5rem 0;
        }
        
        .sample-card {
            background: white;
            border-radius: 8px;
            padding: 1.5rem;
            border: 1px solid var(--border-color);
            box-shadow: 0 2px 4px rgba(0,0,0,0.05);
        }
        
        .sample-card h4 {
            font-size: 1.1rem;
            color: var(--primary-color);
            margin-bottom: 1rem;
            padding-bottom: 0.5rem;
            border-bottom: 1px solid var(--border-color);
        }
        
        .beta-diversity-matrix {
            width: 100%;
            border-collapse: collapse;
            margin: 1.5rem 0;
        }
        
        .beta-diversity-matrix th, .beta-diversity-matrix td {
            padding: 0.5rem;
            text-align: center;
            border: 1px solid var(--border-color);
        }
        
        .beta-diversity-matrix th {
            background-color: var(--light-gray);
            font-weight: 600;
        }
        
        .beta-diversity-matrix td {
            background-color: white;
        }
        
        .beta-value {
            font-weight: 600;
        }
        
        .beta-low {
            background-color: rgba(25, 135, 84, 0.2) !important;
        }
        
        .beta-medium {
            background-color: rgba(255, 193, 7, 0.2) !important;
        }
        
        .beta-high {
            background-color: rgba(220, 53, 69, 0.2) !important;
        }
        
        .calculation-modes {
            display: flex;
            background-color: var(--light-gray);
            border-radius: 6px;
            padding: 4px;
            margin-bottom: 1.5rem;
            flex-wrap: wrap;
        }
        
        .mode-btn {
            flex: 1;
            text-align: center;
            padding: 0.75rem;
            border-radius: 4px;
            cursor: pointer;
            transition: all 0.3s;
            font-weight: 600;
            min-width: 120px;
            margin: 2px;
        }
        
        .mode-btn.active {
            background-color: var(--primary-color);
            color: white;
        }
        
        .mode-form {
            display: none;
        }
        
        .mode-form.active {
            display: block;
        }
        
        .save-case-btn {
            position: absolute;
            top: 10px;
            right: 120px;
        }

        .sample-selection-container {
            background-color: var(--light-gray);
            border-radius: 6px;
            padding: 1.5rem;
            margin: 1.5rem 0;
            border: 1px solid var(--border-color);
        }
        
        .sample-checkbox {
            margin-right: 0.5rem;
        }
        
        .sample-selection-item {
            display: flex;
            align-items: center;
            padding: 0.75rem;
            border-bottom: 1px solid var(--border-color);
        }
        
        .sample-selection-item:last-child {
            border-bottom: none;
        }
        
        .sample-selection-item:hover {
            background-color: rgba(44, 125, 160, 0.05);
        }