:root {
            --primary-color: #2c7da0;
            --secondary-color: #a9d6e5;
            --accent-color: #01497c;
            --light-gray: #f8f9fa;
            --border-color: #eaeaea;
            --text-color: #333;
            --text-muted: #6c757d;
            --success-color: #28a745;
            --warning-color: #ffc107;
        }
         
        .page-header {
            background: linear-gradient(135deg, rgba(169, 214, 229, 0.4) 0%, rgba(44, 125, 160, 0.4) 100%);
            padding: 1.5rem 0;
            margin-bottom: 2rem;
            border-bottom: 1px solid rgba(44, 125, 160, 0.2);
            position: relative;
            overflow: hidden;   color: var(--text-color);
        }
         
        
        .breadcrumb {
            background-color: transparent;
            padding: 0.5rem 0;
            margin-bottom: 0.5rem;
        }
        
        .breadcrumb-item a {
            color: var(--text-muted);
            text-decoration: none;
        }
        
        .breadcrumb-item.active {
            color: var(--text-color);
        }
         
        
        /* Sequence Visualization */
        .sequence-container {
            font-family: 'Courier New', monospace;
            background-color: white;
            border-radius: 6px;
            padding: 1rem;
            margin-bottom: 1rem;
            border: 1px solid var(--border-color);
            overflow-x: auto;
            white-space: nowrap;
        }
        
        .sequence-line {
            line-height: 1.8;
            margin-bottom: 0.5rem;
        }
        
        .sequence-name {
            font-weight: bold;
            color: var(--primary-color);
            min-width: 120px;
            display: inline-block;
        }
        
        .sequence-data {
            letter-spacing: 1px;
        }
        
        .match {
            background-color: rgba(40, 167, 69, 0.2);
            color: #155724;
            padding: 0 2px;
            border-radius: 2px;
        }
        
        .mismatch {
            background-color: rgba(220, 53, 69, 0.2);
            color: #721c24;
            padding: 0 2px;
            border-radius: 2px;
        }
        
        .gap {
            background-color: rgba(108, 117, 125, 0.2);
            color: #383d41;
            padding: 0 2px;
            border-radius: 2px;
        }
        
        /* Alignment Visualization */
        .alignment-container {
            font-family: 'Courier New', monospace;
            background-color: white;
            border-radius: 6px;
            padding: 1rem;
            margin-bottom: 1rem;
            border: 1px solid var(--border-color);
            overflow-x: auto;
        }
        
        .alignment-line {
            line-height: 1.8;
            margin-bottom: 0.5rem;
        }
        
        .consensus-line {
            color: var(--primary-color);
            font-weight: bold;
            margin-top: 0.5rem;
            padding-top: 0.5rem;
            border-top: 1px dashed var(--border-color);
        }
        
        /* Matrix Visualization */
        .matrix-container {
            overflow-x: auto;
            margin: 1.5rem 0;
        }
        
        .matrix-table {
            border-collapse: collapse;
            font-family: 'Courier New', monospace;
            font-size: 0.9rem;
        }
        
        .matrix-table td {
            width: 30px;
            height: 30px;
            text-align: center;
            border: 1px solid #dee2e6;
            padding: 0;
        }
        
        .matrix-table .header {
            background-color: var(--light-gray);
            font-weight: bold;
        }
        
        .matrix-table .path {
            background-color: rgba(44, 125, 160, 0.1);
        }
        
        .matrix-table .max {
            background-color: rgba(40, 167, 69, 0.2);
            font-weight: bold;
        }
        
        /* Statistics Cards */
        .stats-container {
            display: grid;
            grid-template-columns: repeat(auto-fit, minmax(200px, 1fr));
            gap: 1rem;
            margin: 1.5rem 0;
        }
        
        .stat-card {
            background: white;
            border-radius: 8px;
            padding: 1.5rem;
            border: 1px solid var(--border-color);
            box-shadow: 0 2px 4px rgba(0,0,0,0.05);
            text-align: center;
        }
        
        .stat-value {
            font-size: 1.8rem;
            font-weight: 700;
            color: var(--primary-color);
            margin-bottom: 0.5rem;
        }
        
        .stat-label {
            color: var(--text-muted);
            font-size: 0.9rem;
        }
        
        /* Sequence Input */
        .sequence-input {
            font-family: 'Courier New', monospace;
            min-height: 150px;
        }
        
        /* Color coding for nucleotides */
        .A { color: #3498db; font-weight: bold; }
        .T { color: #e74c3c; font-weight: bold; }
        .U { color: #e74c3c; font-weight: bold; }
        .G { color: #f39c12; font-weight: bold; }
        .C { color: #2ecc71; font-weight: bold; }
        
        /* Color coding for amino acids */
        .hydrophobic { color: #3498db; }
        .polar { color: #2ecc71; }
        .acidic { color: #e74c3c; }
        .basic { color: #9b59b6; }
        .special { color: #f39c12; }
        
        /* Demo data indicator */
        .demo-indicator {
            background-color: rgba(255, 193, 7, 0.1);
            border: 1px solid rgba(255, 193, 7, 0.3);
            border-radius: 6px;
            padding: 0.75rem;
            margin-bottom: 1rem;
            display: flex;
            align-items: center;
        }
        
        .demo-indicator i {
            color: #ffc107;
            margin-right: 0.5rem;
        }
 
        
        .comparison-table {
            width: 100%;
            border-collapse: collapse;
        }
        
        .comparison-table th,
        .comparison-table td {
            padding: 0.75rem;
            border: 1px solid var(--border-color);
            text-align: left;
        }
        
        .comparison-table th {
            background-color: var(--light-gray);
            font-weight: 600;
        }
        
      
        
        .parameters-section {
            background-color: rgba(44, 125, 160, 0.03);
            border-radius: 6px;
            padding: 1.5rem;
            margin: 1.5rem 0;
            border: 1px solid rgba(44, 125, 160, 0.1);
        }
        
        .section-divider {
            border-top: 1px solid var(--border-color);
            margin: 2rem 0;
        }